A clinician orders 0.6 g of a drug to be given IV bolus. The solution concentration is 100 mg/mL. How many milliliters are required?

A clinician orders 0.6 g of a drug to be given IV bolus. The solution concentration is 100 mg/mL. How many milliliters are required?

• A. 2 mL
• B. 4 mL
• C. 6 mL
• D. 8 mL

Answer: (C)

Calculating the dose in volume uses the simple relationship: Volume = Dose ÷ Concentration. First convert the prescribed dose to the same units as the concentration: 0.6 g is 600 mg. With a concentration of 100 mg per mL, the required volume is 600 mg ÷ 100 mg/mL = 6 mL. So 6 mL of the solution is needed to deliver the 0.6 g dose as an IV bolus. This approach directly ties together what you’re giving (dose) with how concentrated the solution is (concentration) to determine the correct fluid volume.

Calculating the dose in volume uses the simple relationship: Volume = Dose ÷ Concentration. First convert the prescribed dose to the same units as the concentration: 0.6 g is 600 mg. With a concentration of 100 mg per mL, the required volume is 600 mg ÷ 100 mg/mL = 6 mL. So 6 mL of the solution is needed to deliver the 0.6 g dose as an IV bolus. This approach directly ties together what you’re giving (dose) with how concentrated the solution is (concentration) to determine the correct fluid volume.